(S)-2-Amino-3-(2,4,5-trifluorophenyl)propanoic acid - Names and Identifiers
Name | l-2,4,5-trifluorophenylalanine
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Synonyms | H-Phe(2,4,5-F3)-OH L-2,4,5-Trifluorophe L-2,4,5-TRIFLUOROPHE L-2,4,5-Trifluoro-Phe-OH l-2,4,5-trifluorophenylalanine L-2,4,5-TRIFLUOROPHENYLALANINE 2,4,5-TRIFLUORO-L-PHENYLALANINE -2-Amino-3-(2,4,5-trifluorophenyl) (S)-2-amino-3-(2,4,5-trifluorophenyl)propanoic acid
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CAS | 749847-57-2
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(S)-2-Amino-3-(2,4,5-trifluorophenyl)propanoic acid - Physico-chemical Properties
Molecular Formula | C9H8F3NO2
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Molar Mass | 219.16 |
Density | 1.460±0.06 g/cm3(Predicted) |
Boling Point | 304.1±42.0 °C(Predicted) |
pKa | 2.16±0.25(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
(S)-2-Amino-3-(2,4,5-trifluorophenyl)propanoic acid - Introduction
l-2,4,5-trifluorophenylalanine is an amino acid molecule structurally with the basic skeleton of phenylalanine and three fluorine atoms substituted on the aromatic ring.
Regarding its properties, l-2,4,5-trifluorophenylalanine is a colorless or white solid with low solubility. It is a molecule with chirality and exists in two optical isomers, L-and D-forms.
l-2,4,5-trifluorophenylalanine can be used as an important intermediate and special amino acid in organic synthesis. In drug synthesis, it is often used as a building block for the synthesis of biologically active molecules or drugs. Due to its fluorine substituent, it can change the physicochemical properties of the molecule and increase the stability and bioavailability of the drug.
Regarding the production method, l-2, the synthesis of 4,5-trifluorophenylalanine is usually carried out by a chemical synthesis method. A common method of preparation is the reaction of phenylalanine with a suitable fluorinating reagent to replace the hydrogen atoms on the aromatic ring with fluorine.
In terms of safety, the specific safety information of l-2,4,5-trifluorophenylalanine depends on its use environment and purpose. Chemically, it may cause irritation to the eyes, skin and respiratory tract. Therefore, during use, it is necessary to follow laboratory safety procedures, wear appropriate personal protective equipment, and properly handle and store the compound. During handling and transportation, care needs to be taken to prevent hazards caused by fire sources and electrostatic sparks.
Last Update:2024-04-09 21:54:55